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Isolation of IL12p70-competent human monocyte-derived dendritic cells.

Isolation of IL-12p70-competent human monocyte-derived dendritic cells.
Posted by Curtis

The methodology varies from experimental immunological studies to immunotherapy involves the application of dendritic cells originating from human monocyts (modcs). Variations in the dependent donor are quite large in the production of the MODC IL-12P70 affect the results of this methodology. It has been shown that modcs generated in standard conditions develop into two subsets based on CD1A expression with CD1A + modcs to become the main IL-12P70 manufacturer. But this has not been accepted in general, which we show here because the subset described as CD1A-negative does not reveal CD1A, but at a lower level of other subsets.

We then characterize the phenotype of the two sets of this section, indicating that the CD1A-hi subset has greater immunogenic phenotypes, making this subset more suitable for immunotherapy. The two sets of previous parts have been separated by sorting cells, but because this technique is not available for many laboratories and has incompatibility with clinical settings, more used techniques are guaranteed. Therefore we are tested if cell sorter activated magnetic is useful for this purpose, and shows that it is possible to isolate the CD1A-HI modCs that are competent IL-12P70 with purity <92%, regardless of the initial purity.

Hemohim improves the persistent down rules of immune response such as TH1 in irradiation mice γ fractionation by modulating <em> il </ em> – <amp> 12p70 </ em> signaling paths –stat4.

The mice irradiated throughout the body seem to experience Down rules of immune response T (Th) 1 – such as, and maintain persistent immunological imbalances. In this current study, we evaluate the influence of Hemohim (herbal products made from Angelica Radix, Cnidium Officinale, and Paeonia Japonica which are cultivated in Korea) to improve immunological imbalances caused by irradiation mice. Mice are exposed to rays twice a week (0.5 gy fraction) for a total dose of 5 gy, and hemohim is administered orally from 1 week before the first irradiation up to 1 week before the final analysis. All experiments were carried out 4 and 6 months after their first exposure. Hemohim improves the response of immune related Th1 and Th2 usually occurs in irradiation mice with or without immunization hemocyanin limpet dinitrofenylated.

Hemohim also restored natural killer cell activities without changing the percentage of natural killer cells in irradiation mice. Furthermore, the Hemohim administration prevents the reduction in the level of interleukin-12p70 in irradiation mice. Finally, we found that hemohim increases the phosphorylation of signal transducers and transcription activators (stat) 4 reduced in irradiation mice. Our findings show that Hemohim improves continuous down rules from immune responses like them by modulating the IL-12P70 / Pstat4 signaling path.

Plasma Neonatal Polarized Cytokine Responses mediated by TLR4 towards Low <em> il </ em> 12p70 </ em> and height <em> il </ em> -10 production through different factors.

Human neonates are very susceptible to infection, which will mostly be caused by disruption of the default immune function. Receptor responts such as neonatal toll road (TLR) bias against the generation of pro-inflammatory polarization cytokines / TH1, but the underlying mechanism is incomplete defined. Here, we show that the neonatal plasma is polarized the production of cytokines mediated by TLR4. When exposed to cord blood plasma, mononuclear cells (MCS) produce IL-12P70 mediated by TLR4 significantly and IL-10 higher than the MC exposed to adult plasma. Oppression by neonatal plasma production IL-12P70 mediated TLR4, but not induction of IL-10 production mediated by TLR4, maintained to the age of 1 month.

Plasma blood rope blood provides a similar pattern of the MC cytokine response to TLR3 and TLR8 agonists, showing activity against MYD88 agonists depending on and MYD88-independent. The factor that causes an increase in IL-10 production mediated by TLR4 by plasma blood cables is hot labil, lost after the thinning of protein and independent of the lipoprotein binding protein (LBP) or CD14 (SCD14) dissolves. The factor that causes the inhibition of production of IL-12P70 mediated by TLR4 with blood plasma rope resistant to heat inactivation or depletion of proteins and does not depend on IL-10, vitamin D and prostaglandin e2. In conclusion, neonatal plasma humans contain at least two different factors that suppress the production of IL-12P70 mediated by TLR4 or inducing IL-10 or production. Further identification of these factors will provide insight into ontogeny from default immune development and can identify new targets for prevention and treatment of neonatal infections.

Isolation of <em>IL</em>-<em>12p70</em>-competent human monocyte-derived dendritic cells.

The preparation of the OK432 bacteria induces <em> il </ em> – <em> 12p70 </ em> secretion in human dendritic cells in a way that depends on TLR3.

Dendritic cells (DC) used in immunotherapy therapeutic cancers must be able to stimulate T cells which result in immune responses that can efficiently target cancer cells. One critical obstacle is the lack of production of IL-12P70 when bringing DC, which is repaired using the preparation of the OK432 bacteria (trade name of the Picibanil) to cut the cell. To identify the mechanism behind DC’s OK432 stimulation, we investigate different TLR contributions to check their involvement in the production of IL-12P70. By combining different inhibitors from TLR signaling, we show here that TLR3 is responsible for the production of IL-12P70 DC which is induced by OK432.

Human IL-12p70 ELISA antibody pair

CT750-10 10-plate
EUR 656.4

Human IL-12p70 ELISA antibody pair

CT750-20 20-plate
EUR 1118.4

Human IL-12p70 ELISPOT antibody pair

CT650-10 10-plate
EUR 633.6

Human IL-12p70 ELISPOT antibody pair

CT650-20 20-plate
EUR 1107.6

Human IL-12/IL-23 p40 ELISA Kit

RK00013 96 Tests
EUR 625.2

Human IL-12(p70) ELISA kit

LF-EK50181 1×96T
EUR 777.6

IL-12 p40 ELISA KIT|Human

EF000144 96 Tests
EUR 826.8

IL-12 p35 ELISA KIT|Human

EF007351 96 Tests
EUR 826.8

Human IL-12/P70 ELISA Kit

EHI0362 96Tests
EUR 625.2

Human IL-12 p70 ELISA Kit

RK00014 96 Tests
EUR 625.2

Human IL-12(p70) ELISA kit (4X96T)

LF-EK50182 4×96T
EUR 2641.2

CymaxTM Human IL-12 (p70) ELISA Kit

LF-EK0264 1×96T
EUR 477.6

IL-12 (p70) ELISA Kit (Human) (OKBB00196)

OKBB00196 96 Tests
EUR 606
Description: Description of target: Interleukin (IL)-12 is a 70-KDa cytokine comprised of two disulfide-linked proteins (p35 and p40) and is essential for the initiation of effective immune response.i And the IL-12p70 is a heterodimer of p35 and p40 subunits; it is an important cytokine secreted by antigen-presenting cells in response to antigenic stimulation.ii Gene expression analysis of the IL-12 cytokine family subunits revealed that both strains induced high levels of p40 (protein chain communal to IL-12 p70 and IL-23) as well as p19, a subunit of IL-23. Conversely only ACT- 18HS19 infection induced consistent transcription of IL-12 p35, a subunit of IL-12 p70.iii The standard product used in this kit is recombinant human IL-12 p70 with the molecular mass of 75 KDa.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/ml

IL-12(p40) ELISA Kit (Human) (OKBB00198)

OKBB00198 96 Tests
EUR 606
Description: Description of target: Interleukin-12 (IL12; formerly NKSF, for natural killer cell stimulatory factor, or CLMF, for cytotoxic lymphocyte maturation factor) is a novel cytokine cloned from B-cell lines. IL-12 is a heterodimeric molecule composed of p35 and p40 subunits.1 The larger 40-kDa subunit (p40) is a member of the cytokine receptor family, and the smaller 35-kDa subunit (p35) is related to IL6 and GCSF.2 Both IL-12 p40(-/-) and p35(-/-) mice fail to produce IL-12 p70 heterodimer.3 Interleukin (IL)-12 has been cloned on the basis of its ability to activate natural killer (NK) cells and promote the development of cytolytic T cells. With further understanding of its activities, IL-12 has emerged as an important cytokine, affecting both immune and hematologic functions. It has been shown to be necessary for the T cell independent induction of interferon (IFN)-gamma, critical for the initial suppression of bacterial and parasitic infection; for the development of a Th1 response, critical for effective host defense against intracellular pathogens; and for the activation of differentiated T lymphocytes of both CD4+ and CD8+ phenotype.4 The subunits map to different chromosomes: p40 (IL12B) to 5q31-q33 and p35 (IL12A) to 3p12-3q13.2.2 The standard product used in this kit is recombinant human IL-12(p40), which is a 40KDa glycoprotein consisting of 306 amino acids.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/ml

ELISA kit for Human IL-12 p70

KET6020-48T 48T
EUR 242.4
Description: Quantitative sandwich ELISA for measuring Human IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-12 p70

KET6020-5platesof96wells 5 plates of 96 wells
EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Human IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-12 p70

KET6020-96T 96T
EUR 346.8
Description: Quantitative sandwich ELISA for measuring Human IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Nori® Human IL-12 p35 ELISA Kit

GR111522 96-well
EUR 461

Nori® Human IL-12 p40 ELISA Kit

GR111523 96-well
EUR 461

Human Interleukin 12 P70 (IL-12 p70) ELISA Kit

abx251064-96tests 96 tests
EUR 764.4

Human IL-12(p35)(Interleukin 12 p35) ELISA Kit

EH4146 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human IL-12(p40)(Interleukin 12 p40) ELISA Kit

EH0175 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human IL-12(p70) PicoKine ELISA Kit

EK0421 96 wells
EUR 510
Description: For quantitative detection of human IL-12(P70) in cell culture supernates and serum.

Human IL-12(p40) PicoKine ELISA Kit

EK0423 96 wells
EUR 510
Description: For quantitative detection of human IL-12(P40) in cell culture supernates, serum and plasma(heparin, EDTA, citrate).

IL-12/P40/ Rat IL- 12/ P40 ELISA Kit

ELA-E0058r 96 Tests
EUR 1063.2

IL-12/P70/ Rat IL- 12/ P70 ELISA Kit

ELA-E0059r 96 Tests
EUR 1063.2

Human Interleukin 12,IL-12/P70 ELISA KIT

201-12-0100 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 12,IL-12/P40 ELISA KIT

201-12-0101 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 12, IL-12/P40 ELISA KIT

CSB-E04598h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 12, IL-12/P40 in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 12, IL-12/P40 ELISA KIT

1-CSB-E04598h
  • EUR 722.40
  • EUR 5085.60
  • EUR 2707.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 12, IL-12/P40 in samples from serum, plasma, cell culture supernates, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Interleukin 12, IL-12/P70 ELISA KIT

CSB-E04599h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 12, IL-12/P70 in samples from serum, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 12, IL-12/P70 ELISA KIT

1-CSB-E04599h
  • EUR 723.60
  • EUR 5096.40
  • EUR 2712.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 12, IL-12/P70 in samples from serum, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Interleukin 12,IL-12/P70 ELISA KIT

CN-03218H1 96T
EUR 525.6

Human Interleukin 12,IL-12/P70 ELISA KIT

CN-03218H2 48T
EUR 346.8

Human Interleukin 12,IL-12/P40 ELISA KIT

CN-03219H1 96T
EUR 525.6

Human Interleukin 12,IL-12/P40 ELISA KIT

CN-03219H2 48T
EUR 346.8

Human Interleukin 12,IL-12/P70 ELISA kit

E01I0432-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Interleukin 12,IL-12/P70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Interleukin 12,IL-12/P70 ELISA kit

E01I0432-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Interleukin 12,IL-12/P70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Interleukin 12,IL-12/P70 ELISA kit

E01I0432-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Interleukin 12,IL-12/P70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Interleukin 12(IL-12/P70)ELISA Kit

GA-E0139HM-48T 48T
EUR 346.8

Human Interleukin 12(IL-12/P70)ELISA Kit

GA-E0139HM-96T 96T
EUR 559.2

Human Interleukin 12(IL-12/P40)ELISA Kit

GA-E0140HM-48T 48T
EUR 346.8

Human Interleukin 12(IL-12/P40)ELISA Kit

GA-E0140HM-96T 96T
EUR 559.2

Human Interleukin 12(IL-12/P70)ELISA Kit

QY-E04328 96T
EUR 433.2

Human Interleukin 12(IL-12/P40)ELISA Kit

QY-E04329 96T
EUR 480

Human Interleukin 12,IL-12/P70 ELISA Kit

YLA1522HU-48T 48T
EUR 435

Human Interleukin 12,IL-12/P70 ELISA Kit

YLA1522HU-96T 96T
EUR 562.5

Human Interleukin 12,IL-12/P40 ELISA Kit

YLA1523HU-48T 48T
EUR 435

Human Interleukin 12,IL-12/P40 ELISA Kit

YLA1523HU-96T 96T
EUR 562.5

pAb rabbit anti-human IL-12p70

CT273 0.5 mg
EUR 248.4

mAb mouse anti-human IL-12p70

CT276 0.5 mg
EUR 312

Mouse IL-12/IL-23 p40 ELISA Kit

RK00017 96 Tests
EUR 625.2

ELISA kit for Human IL-12 p35 (Interleukin 12 p35)

E-EL-H1647 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human IL-12 p35 (Interleukin 12 p35) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IL-12 p40 (Interleukin 12 p40)

E-EL-H0151 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human IL-12 p40 (Interleukin 12 p40) in samples from Serum, Plasma, Cell supernatant

Porcine IL-12/IL-23 p40 ELISA Kit

RK00064 96 Tests
EUR 625.2

Human IL-12 p70 ELISA Kit, 96 tests, Quantitative

HIL-012-125 1 kit
EUR 578.4

CymaxTM Mouse IL-12/IL-23 p40 ELISA Kit

LF-EK0297 1×96T
EUR 477.6

Rat IL-12/P70 ELISA Kit

ERI0362 96Tests
EUR 625.2

Goat IL-12/P70 ELISA Kit

EGTI0362 96Tests
EUR 625.2

Mouse IL-12/P70 ELISA Kit

EMI0362 96Tests
EUR 625.2

Mouse IL-27 p28 ELISA Kit

LF-EK50915 1×96T
EUR 777.6

Mouse IL-12(p40) ELISA Kit

LF-EK50957 1×96T
EUR 777.6

Mouse IL-12(p70) ELISA kit

LF-EK50185 1×96T
EUR 777.6

Mouse IL-12 p70 ELISA Kit

RK00018 96 Tests
EUR 625.2

Nori® Ovine IL-30/IL-27 P28 ELISA Kit

GR116143 96-well
EUR 461

Rabbit IL-12/P70 ELISA Kit

ERTI0362 96Tests
EUR 625.2

Bovine IL-12/P70 ELISA Kit

EBI0362 96Tests
EUR 625.2

Canine IL-12/P70 ELISA Kit

ECI0362 96Tests
EUR 625.2

Nori® Equine IL-30/IL-27 P28 ELISA Kit

GR106731 96-well
EUR 461

Nori® Bovine IL-30/IL-27 P28 ELISA Kit

GR112180 96-well
EUR 461

Nori® Canine IL-30/IL-27 P28 ELISA Kit

GR115230 96-well
EUR 461

Porcine IL-12/P70 ELISA Kit

EPI0362 96Tests
EUR 625.2

Nori® Porcine IL-30/IL-27 P28 ELISA Kit

GR113206 96-well
EUR 461

Anserini IL-12/P70 ELISA Kit

EAI0362 96Tests
EUR 625.2

IL-12/p40 ELISA Kit| Rat Interleukin 12 p40 ELISA Kit

EF017838 96 Tests
EUR 826.8

Monkey IL-12/23p40 ELISA kit (detects p40 subunit)

CT149A 5-plate
EUR 554.4

IL-12 p40 ELISA Kit| Mouse Interleukin 12 p40 ELISA Kit

EF013985 96 Tests
EUR 826.8

IL-12 p40 ELISA Kit| Sheep Interleukin 12 p40 ELISA Kit

EF019506 96 Tests
EUR 826.8

Marmoset IL-12/23p40 ELISA kit (detects p40 subunit)

CT345A 5-plate
EUR 554.4

IL-12 p40 ELISA Kit| Porcine Interleukin 12 p40 ELISA Kit

EF016628 96 Tests
EUR 826.8

Human P210 ELISA kit

E01P0162-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human P210 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human P210 ELISA kit

E01P0162-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human P210 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human P210 ELISA kit

E01P0162-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human P210 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Nori® Porcine (pig) IL-12/IL-23 p40 ELISA Kit

GR106161 96-well
EUR 461

Guinea Pig IL-12/P70 ELISA Kit

EGI0362 96Tests
EUR 625.2

Mouse IL-12(p70) ELISA kit (4X96T)

LF-EK50186 4×96T
EUR 2641.2

IL-12 p40 ELISA Kit| Guinea pig Interleukin 12 p40 ELISA Kit

EF012620 96 Tests
EUR 826.8

CymaxTM Mouse IL-12 (p70) ELISA Kit

LF-EK0271 1×96T
EUR 477.6

pAb rabbit anti-human IL-12p70 Biotin-labeled

CT274 0.5 mg
EUR 416.4

IL-12 (p70) ELISA Kit (Mouse) (OKBB00197)

OKBB00197 96 Tests
EUR 606
Description: Description of target: Interleukin (IL)-12 is a 70-KDa cytokine comprised of two disulfide-linked proteins (p35 and p40) and is essential for the initiation of effective immune response. And the IL-12p70 is a heterodimer of p35 and p40 subunits; it is an important cytokine secreted by antigen-presenting cells in response to antigenic stimulation. Gene expression analysis of the IL-12 cytokine family subunits revealed that both strains induced high levels of p40 (protein chain communal to IL-12 p70 and IL-23) as well as p19, a subunit of IL-23. Conversely only ACT- 18HS19 infection induced consistent transcription of IL-12 p35, a subunit of IL-12 p70. The standard product used in this kit is recombinant mouse IL-12 p70 comprising of a 193 amino acids p35 chain and a 313 amino acids p40 chain connected by a disulfide bond.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 1.5 pg/ml

IL-27 p28 ELISA Kit (Mouse) (OKBB00439)

OKBB00439 96 Wells
EUR 606
Description: Description of target: Interleukin-27 (IL-27) is a heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits; Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (also known as IL-27B) and IL27-p28 (known as IL-30). IL-27 is produced by antigen-presenting cells. By genomic sequence analysis, the IL27 p28 gene was mapped to chromosome 16p11. L-27 plays an important function in regulating the activity of B- and T-lymphocytes. The effects of IL-27 are eliciting by its interaction with a specific cell-surface receptor complex composed of two proteins known as IL27R and gp130.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Human P450scc ELISA Kit

EHC0081 96Tests
EUR 625.2

Nori® Rat IL-12 p35 ELISA Kit

GR118364 96-well
EUR 461

Nori® Rat IL-12 p40 ELISA Kit

GR118365 96-well
EUR 461

Rat IL-12/p40(Interleukin 12 p40) ELISA Kit

ER1087 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 7.031pg/ml

Rat IL-12/P70(Interleukin 12(p70)) ELISA Kit

ER1588 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.78pg/ml

ELISA kit for Mouse IL-12 p70

KET7011-48T 48T
EUR 242.4
Description: Quantitative sandwich ELISA for measuring Mouse IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse IL-12 p70

KET7011-5platesof96wells 5 plates of 96 wells
EUR 1292.4
Description: Quantitative sandwich ELISA for measuring Mouse IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse IL-12 p70

KET7011-96T 96T
EUR 346.8
Description: Quantitative sandwich ELISA for measuring Mouse IL-12 p70 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Nori® Goose IL-12 p35 ELISA Kit

GR173046 96-well
EUR 461

Nori® Goose IL-12 p40 ELISA Kit

GR173047 96-well
EUR 461

Nori® Sheep IL-12 p35 ELISA Kit

GR116369 96-well
EUR 461

Nori® Sheep IL-12 p40 ELISA Kit

GR116370 96-well
EUR 461

Nori® Mouse IL-12 p35 ELISA Kit

GR117381 96-well
EUR 461

Nori® Mouse IL-12 p40 ELISA Kit

GR117382 96-well
EUR 461

Mouse IL-12 p40(Interleukin 12 p40) ELISA Kit

EM1470 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml

Human 265PSM ELISA Kit

EHA0675 96Tests
EUR 625.2

p130Cas ELISA KIT|Human

EF008391 96 Tests
EUR 826.8

PI3K p101 ELISA KIT|Human

EF001758 96 Tests
EUR 826.8

Nori® Ferret IL-12 p35 ELISA Kit

GR201154 96-well
EUR 461

Nori® Ferret IL-12 p40 ELISA Kit

GR201155 96-well
EUR 461

Nori® Salmon IL-12 p35 ELISA Kit

GR202154 96-well
EUR 461

Nori® Salmon IL-12 p40 ELISA Kit

GR202155 96-well
EUR 461

Nori® Turkey IL-12 p35 ELISA Kit

GR187147 96-well
EUR 461

Nori® Turkey IL-12 p40 ELISA Kit

GR187148 96-well
EUR 461

Nori® Feline IL-12 P35 ELISA Kit

GR188368 96-well
EUR 461

Nori® Feline IL-12 p40 ELISA Kit

GR188369 96-well
EUR 461

Nori® Equine IL-12 p35 ELISA Kit

GR106972 96-well
EUR 461

Nori® Equine IL-12 p40 ELISA Kit

GR106973 96-well
EUR 461

Nori® Bovine IL-12 p35 ELISA Kit

GR112382 96-well
EUR 461

Nori® Bovine IL-12 p40 ELISA Kit

GR112383 96-well
EUR 461

Nori® Rabbit IL-12 p35 ELISA Kit

GR144345 96-well
EUR 461

Nori® Rabbit IL-12 p40 ELISA Kit

GR144346 96-well
EUR 461

Nori® Monkey IL-12 p35 ELISA Kit

GR169323 96-well
EUR 461

Nori® Monkey IL-12 p40 ELISA Kit

GR169324 96-well
EUR 461

Nori® Donkey IL-12 p35 ELISA Kit

GR170198 96-well
EUR 461

Nori® Donkey IL-12 p40 ELISA Kit

GR170199 96-well
EUR 461

Nori® Canine IL-12 p35 ELISA Kit

GR115473 96-well
EUR 461

Nori® Canine IL-12 p40 ELISA Kit

GR115474 96-well
EUR 461

Porcine IL-12 p40(Interleukin 12 p40) ELISA Kit

EP0087 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Pig;Sensitivity: 28.125pg/ml

Chicken IL-12 p70(Interleukin 12 p70) ELISA Kit

ECH0103 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Chicken;Sensitivity: 9.375pg/ml

Nori® Hamster IL-12 p35 ELISA Kit

GR172308 96-well
EUR 461

Nori® Hamster IL-12 p40 ELISA Kit

GR172309 96-well
EUR 461

In addition, our data shows that ligands that trigger the secretion of IL-12P70 on TLR3 stimulation are sensitive to proteinase and some are also RNASE care. The fact that bacterial compounds such as OK432 can activate the TLR3 path in human DC are new findings. OK432 shows an important ability to induce IL-12P70 production, which is very relevant in DC-based cancer immunotherapy.

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