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Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID – intolerance

Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID - intolerance
Posted by Curtis

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly type 2 inflammatory disease of the upper air ways. A subgroup of patients with CRSwNP suffering from intolerance to nonsteroidal anti-inflammatory drugs (NSAIDs) and developing NSAID-exacerbated respiratory disease (NERD). The purpose of this study was to compare by nasal secretion of inflammatory cytokines endotype CRSwNP patients with and without NSAIDs intolerance.


Method: 20-6 collected nasal secretions of patients suffering from CRSwNP, thirteen with NERD and thirteen without NSAIDs intolerance. As a control, nasal secretions were collected from a healthy donor fifteen. Tryptase and ten Human cyto- kines analyzed: interleukin ( IL ) – 4, IL -5, IL – 6, IL -8, IL – 12p70 , IL -13, IL -17A, IL -23, IFN-g and TNF-a by cytokines multiple arrays on the Luminex 200 platform.


Results: Grade of polyposis and more severe operating frequency of polyps in NERD- compared with non-NERD patients. IL-6 and IL-5 in CRSwNP significantly increased compared to the healthy volunteers. IL-5 and IL-13 were significantly increased in subjects suffering from NERD compared with patients without NERD CRSwNP.
Conclusion: We identified IL-13 as a biomarker may be limited in the nasal secretions of patients with NERD, which allows us to distinguish between CRSwNP with vs without NERD. Characterization endotypes inflammation in CRSwNP allow the introduction of the best available therapy in the context of precision medicine.

Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID - intolerance
Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID – intolerance

Mesenchymal Stem Cell Derived biocompatible membrane vesicles Demonstrate Immunomodulatory Activity Inhibiting activation and proliferation of human mononuclear cells

immune-mediated disease characterized by the abnormal activity of the immune system. B-induced membrane vesicles Cytochalasin (CIMVs) is an innovative therapy instrument. However, the immunomodulatory activity of Human mesenchymal stem cell (MSC) -derived CIMVs (CIMVs-MSCs) are still unknown.

Therefore, we sought to investigate the immunological properties of CIMVs-MSCs and evaluate its effect on Human peripheral blood mononuclear cells (PBMC). We found that CIMVs-MSCs mainly uptaken by monocytes and B-cells. In addition, we show that CIMVs-MSCs inhibit phytohemagglutinin (PHA) induced proliferation of PBMC, with a more pronounced effect on the expansion of T-lymphocytes compared to the B-cell. In addition, the activation of T-helper (CD4 + CD25 +), B-cells (CD19 + CD25 +) and T-cytotoxic lymphocytes (CD8 + CD25 +) were also significantly suppressed by CIMVs-MSC.

Chicken Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ch-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ch-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Eq-48T 48T
EUR 603.6
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Eq-96T 96T
EUR 784.8
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Hu-48T 48T
EUR 374.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Hu-96T 96T
EUR 470.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Mu-48T 48T
EUR 522
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Mu-96T 96T
EUR 673.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-p-48T 48T
EUR 591.6
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-p-96T 96T
EUR 769.2
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ra-48T 48T
EUR 372
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ra-96T 96T
EUR 466.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Rb-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Rb-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Sheep Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Sh-48T 48T
EUR 626.4
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Sheep Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Sh-96T 96T
EUR 817.2
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Si-48T 48T
EUR 626.4
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Si-96T 96T
EUR 817.2
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 4 (IL4) ELISA Kit

RD-IL4-b-48Tests 48 Tests
EUR 592.8

Bovine Interleukin 4 (IL4) ELISA Kit

RD-IL4-b-96Tests 96 Tests
EUR 820.8

Canine Interleukin 4 (IL4) ELISA Kit

RD-IL4-c-48Tests 48 Tests
EUR 566.4

Canine Interleukin 4 (IL4) ELISA Kit

RD-IL4-c-96Tests 96 Tests
EUR 783.6

Chicken Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ch-48Tests 48 Tests
EUR 540

Chicken Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ch-96Tests 96 Tests
EUR 746.4

Equine Interleukin 4 (IL4) ELISA Kit

RD-IL4-Eq-48Tests 48 Tests
EUR 606

Equine Interleukin 4 (IL4) ELISA Kit

RD-IL4-Eq-96Tests 96 Tests
EUR 840

Human Interleukin 4 (IL4) ELISA Kit

RD-IL4-Hu-48Tests 48 Tests
EUR 348

Human Interleukin 4 (IL4) ELISA Kit

RD-IL4-Hu-96Tests 96 Tests
EUR 470.4

Mouse Interleukin 4 (IL4) ELISA Kit

RD-IL4-Mu-48Tests 48 Tests
EUR 514.8

Mouse Interleukin 4 (IL4) ELISA Kit

RD-IL4-Mu-96Tests 96 Tests
EUR 709.2

Porcine Interleukin 4 (IL4) ELISA Kit

RD-IL4-p-48Tests 48 Tests
EUR 592.8

Porcine Interleukin 4 (IL4) ELISA Kit

RD-IL4-p-96Tests 96 Tests
EUR 820.8

Rat Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ra-48Tests 48 Tests
EUR 345.6

Rat Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ra-96Tests 96 Tests
EUR 468

Rabbit Interleukin 4 (IL4) ELISA Kit

RD-IL4-Rb-48Tests 48 Tests
EUR 540

Rabbit Interleukin 4 (IL4) ELISA Kit

RD-IL4-Rb-96Tests 96 Tests
EUR 746.4

Sheep Interleukin 4 (IL4) ELISA Kit

RD-IL4-Sh-48Tests 48 Tests
EUR 632.4

Sheep Interleukin 4 (IL4) ELISA Kit

RD-IL4-Sh-96Tests 96 Tests
EUR 877.2

Monkey Interleukin 4 (IL4) ELISA Kit

RD-IL4-Si-48Tests 48 Tests
EUR 632.4

Monkey Interleukin 4 (IL4) ELISA Kit

RD-IL4-Si-96Tests 96 Tests
EUR 877.2

Bovine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-b-48Tests 48 Tests
EUR 619.2

Bovine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-b-96Tests 96 Tests
EUR 859.2

Canine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-c-48Tests 48 Tests
EUR 591.6

Canine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-c-96Tests 96 Tests
EUR 819.6

Chicken Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ch-48Tests 48 Tests
EUR 564

Chicken Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ch-96Tests 96 Tests
EUR 781.2

Equine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Eq-48Tests 48 Tests
EUR 633.6

Equine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Eq-96Tests 96 Tests
EUR 879.6

Human Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Hu-48Tests 48 Tests
EUR 362.4

Human Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Hu-96Tests 96 Tests
EUR 490.8

Mouse Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Mu-48Tests 48 Tests
EUR 536.4

Mouse Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Mu-96Tests 96 Tests
EUR 741.6

Porcine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-p-48Tests 48 Tests
EUR 619.2

Porcine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-p-96Tests 96 Tests
EUR 859.2

Rat Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ra-48Tests 48 Tests
EUR 360

Rat Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ra-96Tests 96 Tests
EUR 488.4

Rabbit Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Rb-48Tests 48 Tests
EUR 564

Rabbit Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Rb-96Tests 96 Tests
EUR 781.2

Sheep Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Sh-48Tests 48 Tests
EUR 661.2

Sheep Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Sh-96Tests 96 Tests
EUR 918

Monkey Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Si-48Tests 48 Tests
EUR 661.2

Monkey Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Si-96Tests 96 Tests
EUR 918

Guinea pig Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Gu-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Gu-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 4 (IL4) ELISA Kit

RD-IL4-Gu-48Tests 48 Tests
EUR 566.4

Guinea pig Interleukin 4 (IL4) ELISA Kit

RD-IL4-Gu-96Tests 96 Tests
EUR 783.6

Guinea pig Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Gu-48Tests 48 Tests
EUR 591.6

Guinea pig Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Gu-96Tests 96 Tests
EUR 819.6

Interleukin 4 (IL4) Polyclonal Antibody (Dog)

4-PAA077Ca01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Chicken)

4-PAA077Ga01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Chicken Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu01
  • EUR 290.40
  • EUR 2932.80
  • EUR 732.00
  • EUR 364.80
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu02
  • EUR 225.60
  • EUR 1903.20
  • EUR 498.00
  • EUR 271.20
  • EUR 225.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu06
  • EUR 235.20
  • EUR 2061.60
  • EUR 534.00
  • EUR 285.60
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Mouse)

4-PAA077Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Mouse)

4-PAA077Mu06
  • EUR 298.80
  • EUR 3058.80
  • EUR 760.80
  • EUR 375.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Pig)

4-PAA077Po01
  • EUR 310.80
  • EUR 3232.80
  • EUR 800.40
  • EUR 391.20
  • EUR 261.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rat)

4-PAA077Ra01
  • EUR 224.40
  • EUR 1886.40
  • EUR 494.40
  • EUR 268.80
  • EUR 225.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rat)

4-PAA077Ra06
  • EUR 224.40
  • EUR 1886.40
  • EUR 494.40
  • EUR 268.80
  • EUR 225.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rabbit)

4-PAA077Rb51
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Guinea polyclonal antibody against Rabbit Interleukin 4 (IL4)

Interleukin 4 (IL4) Antibody

20-abx100944
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx100945
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx100946
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx100947
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx100948
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx109942
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx110541
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx104769
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx104913
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx173160
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173161
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173162
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173163
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173164
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173165
  • EUR 1111.20
  • EUR 560.40
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173166
  • EUR 1144.80
  • EUR 577.20
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx173167
  • EUR 1144.80
  • EUR 577.20
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

abx148481-100ug 100 ug
EUR 526.8

Interleukin 4 (IL4) Antibody

20-abx137090
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Interleukin 4 (IL4) Antibody

20-abx137097
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Interleukin 4 (IL4) Antibody

20-abx130731
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx130732
  • EUR 510.00
  • EUR 159.60
  • EUR 1462.80
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx130733
  • EUR 376.80
  • EUR 159.60
  • EUR 1028.40
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx130734
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx131748
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx129505
  • EUR 360.00
  • EUR 159.60
  • EUR 927.60
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx006302
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Interleukin 4 (IL4) Antibody

20-abx015093
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Interleukin 4 (IL4) Antibody

20-abx009115
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 4 (IL4) Antibody

20-abx009116
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 4 (IL4) Antibody

20-abx009117
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Interleukin 4 (IL4) Antibody

abx032452-400ul 400 ul
EUR 627.6

Interleukin 4 (IL4) Antibody

abx032452-80l 80 µl
EUR 343.2

Interleukin 4 (IL4) Antibody

abx037033-100ug 100 ug
EUR 469.2

Interleukin 4 (IL4) Antibody

20-abx200977
  • EUR 376.80
  • EUR 594.00
  • 100 ug
  • 500 ug

Interleukin 4 (IL4) Antibody

abx234278-100ug 100 ug
EUR 661.2

Interleukin 4 (IL4) Antibody

abx330739-100ul 100 ul
EUR 510

Interleukin 4 (IL4) Antibody

20-abx270159
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 4 (IL4) Antibody

20-abx270232
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Interleukin 4 (IL4) Antibody

20-abx323730
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx324014
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx324053
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx318199
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 4 (IL4) Antibody

20-abx177170
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177172
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177173
  • EUR 1545.60
  • EUR 744.00
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177174
  • EUR 1579.20
  • EUR 760.80
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177175
  • EUR 1579.20
  • EUR 760.80
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177176
  • EUR 1646.40
  • EUR 777.60
  • 1 mg
  • 200 ug

Interleukin 4 (IL4) Antibody

20-abx177177
  • EUR 1646.40
  • EUR 777.60
  • 1 mg
  • 200 ug

Eukaryotic Interleukin 4 (IL4)

4-EPA077Hu61
  • EUR 831.78
  • EUR 346.80
  • EUR 2789.18
  • EUR 1009.73
  • EUR 1899.46
  • EUR 632.40
  • EUR 6792.96
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 4 expressed in: 293F cell

Eukaryotic Interleukin 4 (IL4)

4-EPA077Mu61
  • EUR 872.64
  • EUR 357.60
  • EUR 2942.40
  • EUR 1060.80
  • EUR 2001.60
  • EUR 660.00
  • EUR 7176.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Interleukin 4 expressed in: 293F cell

Eukaryotic Interleukin 4 (IL4)

4-EPA077Ra61
  • EUR 874.79
  • EUR 357.60
  • EUR 2950.46
  • EUR 1063.49
  • EUR 2006.98
  • EUR 661.20
  • EUR 7196.16
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Interleukin 4 expressed in: 293F cell

Active Interleukin 4 (IL4)

4-APA077Hu01
  • EUR 798.46
  • EUR 337.20
  • EUR 2664.19
  • EUR 968.06
  • EUR 1816.13
  • EUR 609.60
  • EUR 6480.48
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 4 expressed in: E.coli

Active Interleukin 4 (IL4)

4-APA077Hu61
  • EUR 939.30
  • EUR 375.60
  • EUR 3192.38
  • EUR 1144.13
  • EUR 2168.26
  • EUR 704.40
  • EUR 7800.96
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 4 expressed in: 293F cell

Active Interleukin 4 (IL4)

4-APA077Mu01
  • EUR 781.25
  • EUR 332.40
  • EUR 2599.68
  • EUR 946.56
  • EUR 1773.12
  • EUR 598.80
  • EUR 6319.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Interleukin 4 expressed in: E.coli

Active Interleukin 4 (IL4)

4-APA077Ra01
  • EUR 995.21
  • EUR 390.00
  • EUR 3402.05
  • EUR 1214.02
  • EUR 2308.03
  • EUR 741.60
  • EUR 8325.12
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Interleukin 4 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Recombinant Interleukin 4 (IL4)

4-RPA077Ca01
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Dog Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Ga01
  • EUR 612.44
  • EUR 286.80
  • EUR 1966.66
  • EUR 735.55
  • EUR 1351.10
  • EUR 484.80
  • EUR 4736.64
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Chicken Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Hu02
  • EUR 642.55
  • EUR 295.20
  • EUR 2079.55
  • EUR 773.18
  • EUR 1426.37
  • EUR 505.20
  • EUR 5018.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Mu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Po01
  • EUR 689.86
  • EUR 308.40
  • EUR 2256.96
  • EUR 832.32
  • EUR 1544.64
  • EUR 537.60
  • EUR 5462.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Ra01
  • EUR 605.99
  • EUR 285.60
  • EUR 1942.46
  • EUR 727.49
  • EUR 1334.98
  • EUR 481.20
  • EUR 4676.16
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Interleukin 4 expressed in: E.coli

Recombinant Interleukin 4 (IL4)

4-RPA077Rb01
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rabbit Interleukin 4 expressed in: E.coli

Interleukin 4 (IL4) Polyclonal Antibody (Dog), APC

4-PAA077Ca01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 4 (IL4). This antibody is labeled with APC.

Interleukin 4 (IL4) Polyclonal Antibody (Dog), Biotinylated

4-PAA077Ca01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 4 (IL4). This antibody is labeled with Biotin.

Additionally, CIMVs-MSCs decrease in the secretion of a factor of epidermal growth (EGF) and fractalkine pro-inflammatory in the population of PBMCs, while the release of FGF-2, G-CSF, anti-inflammatory GM-CSF, MCP-3, anti-inflammatory MDC, anti -inflamasi IL – 12p70 , a pro-inflammatory IL -1b, and MCP-1 increased. We analyzed the effect of CIMVs-MSCs in isolated populations of CD4 + and CD8 + T-lymphocytes and show a different immune response and cytokine secretion. Finally, we observe that there is no xenogeneic or allogeneic transplantation of CIMVs induced immune responses in mice. Our data show that CIMVs-MSCs have immunosuppressive properties, is a potential agent for immunomodulatory treatment, and worthy of further investigation.

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