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Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID – intolerance

Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID - intolerance
Posted by Curtis

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly type 2 inflammatory disease of the upper air ways. A subgroup of patients with CRSwNP suffering from intolerance to nonsteroidal anti-inflammatory drugs (NSAIDs) and developing NSAID-exacerbated respiratory disease (NERD). The purpose of this study was to compare by nasal secretion of inflammatory cytokines endotype CRSwNP patients with and without NSAIDs intolerance.


Method: 20-6 collected nasal secretions of patients suffering from CRSwNP, thirteen with NERD and thirteen without NSAIDs intolerance. As a control, nasal secretions were collected from a healthy donor fifteen. Tryptase and ten Human cyto- kines analyzed: interleukin ( IL ) – 4, IL -5, IL – 6, IL -8, IL – 12p70 , IL -13, IL -17A, IL -23, IFN-g and TNF-a by cytokines multiple arrays on the Luminex 200 platform.


Results: Grade of polyposis and more severe operating frequency of polyps in NERD- compared with non-NERD patients. IL-6 and IL-5 in CRSwNP significantly increased compared to the healthy volunteers. IL-5 and IL-13 were significantly increased in subjects suffering from NERD compared with patients without NERD CRSwNP.
Conclusion: We identified IL-13 as a biomarker may be limited in the nasal secretions of patients with NERD, which allows us to distinguish between CRSwNP with vs without NERD. Characterization endotypes inflammation in CRSwNP allow the introduction of the best available therapy in the context of precision medicine.

Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID - intolerance
Endotypes of chronic rhinosinusitis with nasal polyps with and without NSAID – intolerance

Mesenchymal Stem Cell Derived biocompatible membrane vesicles Demonstrate Immunomodulatory Activity Inhibiting activation and proliferation of human mononuclear cells

immune-mediated disease characterized by the abnormal activity of the immune system. B-induced membrane vesicles Cytochalasin (CIMVs) is an innovative therapy instrument. However, the immunomodulatory activity of Human mesenchymal stem cell (MSC) -derived CIMVs (CIMVs-MSCs) are still unknown.

Therefore, we sought to investigate the immunological properties of CIMVs-MSCs and evaluate its effect on Human peripheral blood mononuclear cells (PBMC). We found that CIMVs-MSCs mainly uptaken by monocytes and B-cells. In addition, we show that CIMVs-MSCs inhibit phytohemagglutinin (PHA) induced proliferation of PBMC, with a more pronounced effect on the expansion of T-lymphocytes compared to the B-cell. In addition, the activation of T-helper (CD4 + CD25 +), B-cells (CD19 + CD25 +) and T-cytotoxic lymphocytes (CD8 + CD25 +) were also significantly suppressed by CIMVs-MSC.

Canine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-c-48T 48T
EUR 474
  • Should the Canine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-c-96T 96T
EUR 614
  • Should the Canine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ch-48T 48T
EUR 454
  • Should the Chicken Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ch-96T 96T
EUR 587
  • Should the Chicken Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Eq-48T 48T
EUR 503
  • Should the Equine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Eq-96T 96T
EUR 654
  • Should the Equine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Hu-48T 48T
EUR 312
  • Should the Human Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Hu-96T 96T
EUR 392
  • Should the Human Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Mu-48T 48T
EUR 435
  • Should the Mouse Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Mu-96T 96T
EUR 561
  • Should the Mouse Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-p-48T 48T
EUR 493
  • Should the Porcine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 4 (IL4) ELISA Kit

DLR-IL4-p-96T 96T
EUR 641
  • Should the Porcine Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ra-48T 48T
EUR 310
  • Should the Rat Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Ra-96T 96T
EUR 389
  • Should the Rat Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Rb-48T 48T
EUR 454
  • Should the Rabbit Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Rb-96T 96T
EUR 587
  • Should the Rabbit Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Sheep Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Sh-48T 48T
EUR 522
  • Should the Sheep Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Sheep Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Sh-96T 96T
EUR 681
  • Should the Sheep Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Sheep Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Si-48T 48T
EUR 522
  • Should the Monkey Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Monkey Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Si-96T 96T
EUR 681
  • Should the Monkey Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-b-48Tests 48 Tests
EUR 516

Bovine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-b-96Tests 96 Tests
EUR 716

Canine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-c-48Tests 48 Tests
EUR 493

Canine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-c-96Tests 96 Tests
EUR 683

Chicken Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ch-48Tests 48 Tests
EUR 470

Chicken Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ch-96Tests 96 Tests
EUR 651

Equine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Eq-48Tests 48 Tests
EUR 528

Equine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Eq-96Tests 96 Tests
EUR 733

Human Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Hu-48Tests 48 Tests
EUR 302

Human Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Hu-96Tests 96 Tests
EUR 409

Mouse Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Mu-48Tests 48 Tests
EUR 447

Mouse Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Mu-96Tests 96 Tests
EUR 618

Porcine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-p-48Tests 48 Tests
EUR 516

Porcine Interleukin 4 (IL4) ELISA Kit

RDR-IL4-p-96Tests 96 Tests
EUR 716

Rat Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ra-48Tests 48 Tests
EUR 300

Rat Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Ra-96Tests 96 Tests
EUR 407

Rabbit Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Rb-48Tests 48 Tests
EUR 470

Rabbit Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Rb-96Tests 96 Tests
EUR 651

Sheep Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Sh-48Tests 48 Tests
EUR 551

Sheep Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Sh-96Tests 96 Tests
EUR 765

Monkey Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Si-48Tests 48 Tests
EUR 551

Monkey Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Si-96Tests 96 Tests
EUR 765

Bovine Interleukin 4 (IL4) ELISA Kit

RD-IL4-b-48Tests 48 Tests
EUR 494

Bovine Interleukin 4 (IL4) ELISA Kit

RD-IL4-b-96Tests 96 Tests
EUR 684

Canine Interleukin 4 (IL4) ELISA Kit

RD-IL4-c-48Tests 48 Tests
EUR 472

Canine Interleukin 4 (IL4) ELISA Kit

RD-IL4-c-96Tests 96 Tests
EUR 653

Chicken Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ch-48Tests 48 Tests
EUR 450

Chicken Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ch-96Tests 96 Tests
EUR 622

Equine Interleukin 4 (IL4) ELISA Kit

RD-IL4-Eq-48Tests 48 Tests
EUR 505

Equine Interleukin 4 (IL4) ELISA Kit

RD-IL4-Eq-96Tests 96 Tests
EUR 700

Human Interleukin 4 (IL4) ELISA Kit

RD-IL4-Hu-48Tests 48 Tests
EUR 290

Human Interleukin 4 (IL4) ELISA Kit

RD-IL4-Hu-96Tests 96 Tests
EUR 392

Mouse Interleukin 4 (IL4) ELISA Kit

RD-IL4-Mu-48Tests 48 Tests
EUR 429

Mouse Interleukin 4 (IL4) ELISA Kit

RD-IL4-Mu-96Tests 96 Tests
EUR 591

Porcine Interleukin 4 (IL4) ELISA Kit

RD-IL4-p-48Tests 48 Tests
EUR 494

Porcine Interleukin 4 (IL4) ELISA Kit

RD-IL4-p-96Tests 96 Tests
EUR 684

Rat Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ra-48Tests 48 Tests
EUR 288

Rat Interleukin 4 (IL4) ELISA Kit

RD-IL4-Ra-96Tests 96 Tests
EUR 390

Rabbit Interleukin 4 (IL4) ELISA Kit

RD-IL4-Rb-48Tests 48 Tests
EUR 450

Rabbit Interleukin 4 (IL4) ELISA Kit

RD-IL4-Rb-96Tests 96 Tests
EUR 622

Sheep Interleukin 4 (IL4) ELISA Kit

RD-IL4-Sh-48Tests 48 Tests
EUR 527

Sheep Interleukin 4 (IL4) ELISA Kit

RD-IL4-Sh-96Tests 96 Tests
EUR 731

Monkey Interleukin 4 (IL4) ELISA Kit

RD-IL4-Si-48Tests 48 Tests
EUR 527

Monkey Interleukin 4 (IL4) ELISA Kit

RD-IL4-Si-96Tests 96 Tests
EUR 731

Guinea pig Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Gu-48T 48T
EUR 474
  • Should the Guinea pig Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 4 (IL4) ELISA Kit

DLR-IL4-Gu-96T 96T
EUR 614
  • Should the Guinea pig Interleukin 4 (IL4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 4 (IL4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Gu-48Tests 48 Tests
EUR 493

Guinea pig Interleukin 4 (IL4) ELISA Kit

RDR-IL4-Gu-96Tests 96 Tests
EUR 683

Guinea pig Interleukin 4 (IL4) ELISA Kit

RD-IL4-Gu-48Tests 48 Tests
EUR 472

Guinea pig Interleukin 4 (IL4) ELISA Kit

RD-IL4-Gu-96Tests 96 Tests
EUR 653

Interleukin 4 (IL4) Polyclonal Antibody (Dog)

4-PAA077Ca01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (Gly24~His132)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Chicken)

4-PAA077Ga01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (Leu26~Lys136)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Chicken Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu01
  • EUR 242.00
  • EUR 2444.00
  • EUR 610.00
  • EUR 304.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: His25~Ser153
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu02
  • EUR 188.00
  • EUR 1586.00
  • EUR 415.00
  • EUR 226.00
  • EUR 188.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (His25~Ser153)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Human)

4-PAA077Hu06
  • EUR 196.00
  • EUR 1718.00
  • EUR 445.00
  • EUR 238.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (His25~Ser153)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Mouse)

4-PAA077Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (His23~Ser140)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Mouse)

4-PAA077Mu06
  • EUR 249.00
  • EUR 2549.00
  • EUR 634.00
  • EUR 313.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (His21~Ser140)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Pig)

4-PAA077Po01
  • EUR 259.00
  • EUR 2694.00
  • EUR 667.00
  • EUR 326.00
  • EUR 218.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (His25~Cys133)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Pig Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rat)

4-PAA077Ra01
  • EUR 187.00
  • EUR 1572.00
  • EUR 412.00
  • EUR 224.00
  • EUR 188.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (Asn61~Leu111)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rat)

4-PAA077Ra06
  • EUR 187.00
  • EUR 1572.00
  • EUR 412.00
  • EUR 224.00
  • EUR 188.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IL4 (Cys25~Ser147)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Interleukin 4 (IL4)

Interleukin 4 (IL4) Polyclonal Antibody (Rabbit)

4-PAA077Rb51
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Arg26~Ser147
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Guinea polyclonal antibody against Rabbit Interleukin 4 (IL4)

Interleukin 4 (IL4) Antibody

20-abx009115
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Interleukin 4 (IL4) Antibody

20-abx009116
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Interleukin 4 (IL4) Antibody

20-abx009117
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Interleukin 4 (IL4) Antibody

20-abx006302
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Interleukin 4 (IL4) Antibody

20-abx015093
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Interleukin 4 (IL4) Antibody

20-abx177170
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177172
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177173
  • EUR 1288.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177174
  • EUR 1316.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177175
  • EUR 1316.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177176
  • EUR 1372.00
  • EUR 648.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx177177
  • EUR 1372.00
  • EUR 648.00
  • 1 mg
  • 200 ug
  • Please enquire.

Interleukin 4 (IL4) Antibody

20-abx200977
  • EUR 314.00
  • EUR 495.00
  • 100 ug
  • 500 ug
  • Shipped within 2-3 weeks.

Interleukin 4 (IL4) Antibody

20-abx100944
  • EUR 300.00
  • EUR 133.00
  • EUR 787.00
  • EUR 411.00
  • EUR 258.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Interleukin 4 (IL4) Antibody

20-abx100945
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Interleukin 4 (IL4) Antibody

20-abx100946
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-7 working days.

Interleukin 4 (IL4) Antibody

20-abx100947
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Additionally, CIMVs-MSCs decrease in the secretion of a factor of epidermal growth (EGF) and fractalkine pro-inflammatory in the population of PBMCs, while the release of FGF-2, G-CSF, anti-inflammatory GM-CSF, MCP-3, anti-inflammatory MDC, anti -inflamasi IL – 12p70 , a pro-inflammatory IL -1b, and MCP-1 increased. We analyzed the effect of CIMVs-MSCs in isolated populations of CD4 + and CD8 + T-lymphocytes and show a different immune response and cytokine secretion. Finally, we observe that there is no xenogeneic or allogeneic transplantation of CIMVs induced immune responses in mice. Our data show that CIMVs-MSCs have immunosuppressive properties, is a potential agent for immunomodulatory treatment, and worthy of further investigation.

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