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Interleukin-12 ( il 12p70 ) promotes induction of CD25 (+) CD25 (+) which is very strong (+) cell regulations that inhibit the refusal of allograft on the recipient that is not modified.

Interleukin-12 ( il - 12p70 ) promotes induction of CD25 (+) CD25 (+) which is very strong (+) cell regulations that inhibit the refusal of allograft on the recipient that is not modified.
Posted by Curtis

In the Mouse Model, CD4 (+) CD25 (+) Cell Regulation (TREG) plays a key role in induction and maintenance of special antigen transplant tolerance, especially in DA mice with PVG Heart Allografts (1, 2). We have described the generation of special treg alloantigen (TS1), with CD25 (+) CD25 (+) culture (+) Naïve (+) Treg (NTREG) with allOantigen and certain IL-2 for 4 days.

These cells express mRNA for IFN-γ receptors (ifngr) and suppress donors but not the refusal of third-party allograft heart mediated by cell t alloreactive CD4 (+) in the ratio <1:10. Here, we showed that TS1 also stated that specific receptors IL-12P70 (IL-12Rβ2) and RIL-12P70 could induce their proliferation. TS1 cells are financially refined with RIL-12P70 alone or RIL-12P70 and recombinant interlukin-2 (RIL-2), pressing CD4 (+) cell proliferation in mixed lymphocyte culture at <1: 1024, while TS1 cells are cultured again with RIL- 2 and alloantigen are only pressed at 1: 32-64.

TS1 cells issued by the RIL-12P70 are significantly delaying PVG, but not a third party Lewis, the refusal of the heart allograft on the recipient and normal. TS1 cells are cultured back for 4 days with RIL-12P70 only, but not cultivated with the RIL-12P70 and RIL-2, declaring more IL-12Rβ2, T-bets, and IFN-γ, and continues to express the TS1 cell markers, FOXP3, IFNGR, and IL-5 which shows treg like TH1 induced. TS1 cells are cultivated with RIL-2 and alloantigens remain from the Fenotype TS1 and do not suppress the rejection of the heart graft in normal mice. We induce Treg which is very similar to Naïve Naïve in 7 days with a culture with alloantigen, first with RIL-2 then with the RIL-12P70. This treg th1-like is delaying the refusal of specific allograft donors that show therapeutic potential.

Rapamycin added DC <br> <br> </ em> – <em> 12p70 </ em> and <em> il </ em> -27 secretion to promote allogenic type 1 polarization modulated by NK cells.

The target of mammals from Rapamycin Inhibitor (MTori) Rapamycin (Rapa) used in transplants can cause inflammatory complications in several patients. Our goal is to better understand how the monocyte dendritic cells that are reduced by MTori Man (DC) are stimulated with pro-inflammatory cytokines forming a single cell allo immunity. Rapa-Conditioned-DC (Rapa-DC) displays more immature phenotypes than untreated, control (Ctrl) -DC. However, the further Rapa-DC exposure to the Cytokin Inflammatory Cocktail (ICC) plus IFN-γ induces mature type-1 promotional phenotypes, which consist of an increase in HLA-DR and mutual stimulation molecules, augmented IL-12P70 and IL-27 production, but Decrease in IL-10 secretion compared to CTRL-DC.

CO-CULTURE OF MATURE (M) Rapa-DC with mononuclear blood cells Allogenic peripheral produces type-1 (IFN-γ) responses increases with T cells. In addition, NK cells act as a default modulator that delivers activating contact signals cell-to-cells besides helpers (IFN-γ) and / or Regulation (IL-10) are soluble in cytokines. We conclude that the production of IL12-P70, IL-27 and Low IL-10 by Rapa-DC allows us to explain how this cytokine and NK-DC interactions form immunity cells. Thus, the lack of NK cell function obstacles during activation of all-specific T cells by RAPA-DC ICC + IFN-γ-γ can represent an unwanted effector mechanism that can underlie the inflammatory events induced by transplant patients undergoing microbial infections or rejection Allograft. ,

Augmentation of antitumor immunity by tumor cell fusion treated ethanol and dendritic cells stimulates through dual tlrs through tgf-β1 blockade and <em> il </ em> – <em> 12p70 </ em> production.

The therapeutic efficacy of the fusion cell cancer vaccine (FC) produced by all tumor cells and dendritic cells (DCS) requires an increase in the immunogenicity of the two cells. Treatment of all tumor cells with ethanol produce the blockade of soluble-suppressive factors such as the transformation of growth factors (TGF) -β1, the growth factor of vascular endothelial, and IL-10 without a decrease in the ultimate class I complex (MHC) class I and antigens related to tumors MUC1. In addition, tumor cells treated ethanol expresses the signal of “eat-me” such as Calretulin (CRT) on the cell surface and releases immunostimulator factors such as heat protein shock (HSP) 90α and HMGB1 group box).

Interleukin-12 (<em> il </ em> - <em> 12p70 </ em>) promotes induction of CD25 (+) CD25 (+) which is very strong (+) cell regulations that inhibit the refusal of allograft on the recipient that is not modified.

Double stimulation Polysaccharides The bound protein isolated from the Coriolus Versicolor (TLR2 agonist) and the non-active streptococcus pyogenes (TLR4 agonists) lead DC monocyte-human derivative to produce HSP90α and several cytokines such as IL-12P70 and IL-10. Interestingly, combining tumor cells treated ethanol and DCS which are stimulated by TLR during the fusion process promoting fusion efficiency and class II MHC molecules which are set on a per fusion basis. In addition, fusion of tumor cells treated with ethanol and DCS is stimulated dual TLR (e-tumor / FCS) inhibiting the production of several immune suppressor factors including TGF-β1 and increase the production of IL-12P70 and HSP90α.

IL-4 High Sensitivity ELISA Kit (Human) (OKDB00045)

OKDB00045 1x96Wells
EUR 787
Description: Description of target: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.31 pg/mL

IL-6 High Sensitivity ELISA Kit (Human) (OKDB00046)

OKDB00046 1x96Wells
EUR 787
Description: Description of target: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.81 pg/mL

IL-10 High Sensitivity Kit (Human) (OKDB00042)

OKDB00042 1x96Wells
EUR 774
Description: Description of target: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.98 pg/mL

Rat IL-12P70 ELISA Kit

DEIA1175 96T
EUR 944
Description: The Rat IL-12P70 ELISA kit is designed to detect and quantify the level of Rat IL-12P70 in cell culture supernatant, serum, plasma and tissue. This kit is for research use only and not intended for diagnostic purposes.

Human IL-12p70 ELISPOT kit

CT240-PB2 2-plate
EUR 415

Human IL-12p70 ELISPOT kit

CT240-PB5 5-plate
EUR 568

Human IL-12p70 ELISPOT kit

CT240-PR2 2-plate
EUR 415

Human IL-12p70 ELISPOT kit

CT240-PR5 5-plate
EUR 556

Human IL-12p70 ELISPOT kit

CT240-T2 2-plate
EUR 360

Human IL-12p70 ELISPOT kit

CT240-T5 5-plate
EUR 579

IL-1 alpha High Sensitivity ELISA Kit (Goat) (OKCD01302)

OKCD01302 96 Wells
EUR 1053
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.;Species reactivity: Goat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.32 pg/mL

Human IL-12p70 ELISA antibody pair

CT750-10 10-plate
EUR 547

Human IL-12p70 ELISA antibody pair

CT750-20 20-plate
EUR 932

Human EGF ELISA Kit (High Sensitivity)

RK00024HS 96 Tests
EUR 587

HSP70 ELISA Kit (High-Sensitivity)

abx259904-96well 96 well
EUR 1083
  • Shipped within 5-12 working days.

HSP70 ELISA Kit (High-Sensitivity)

EK7109 96wells/kit, with removable strips.
EUR 758

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-480 5 plates of 96 wells
EUR 2702
  • HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas
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Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

HSP70 ELISA Kit (High-Sensitivity)

SKT-108-96 1 plate of 96 wells
EUR 685
  • HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas
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Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

pAb rabbit anti-human IL-12p70

CT273 0.5 mg
EUR 207

mAb mouse anti-human IL-12p70

CT276 0.5 mg
EUR 260

Human IL-12p70 ELISPOT antibody pair

CT650-10 10-plate
EUR 528

Human IL-12p70 ELISPOT antibody pair

CT650-20 20-plate
EUR 923

High-sensitivity Human Growth Hormone ELISA Kit

DEIA449 96T
EUR 679
Description: Thishigh-sensitivity Human Growth Hormone ELISA Kit is to be used for the invitro quantitative determination of human growth hormone (hGH) concentrationsin serum.

IL2 High Sensitivity ELISA Kit (Human) (OKCD01305)

OKCD01305 96 Wells
EUR 714
Description: Description of target: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.51 pg/mL

IL6 High Sensitivity ELISA Kit (Human) (OKCD01308)

OKCD01308 96 Wells
EUR 648
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 pg/mL

IL8 High Sensitivity ELISA Kit (Human) (OKCD01311)

OKCD01311 96 Wells
EUR 648
Description: Description of target: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.7 pg/mL

LN High Sensitivity ELISA Kit (Human) (OKCD01312)

OKCD01312 96 Wells
EUR 831
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

MMP13 High Sensitivity ELISA Kit (Human) (OKCD01314)

OKCD01314 96 Wells
EUR 831
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.1;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 12.1 pg/mL

NGF High Sensitivity ELISA Kit (Human) (OKCD01316)

OKCD01316 96 Wells
EUR 727
Description: Description of target: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.97 pg/mL

TNF High Sensitivity ELISA Kit (Human) (OKCD01318)

OKCD01318 96 Wells
EUR 714
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.49 pg/mL

TFPI High Sensitivity ELISA Kit (Human) (OKCD01321)

OKCD01321 96 Wells
EUR 596
Description: Description of target: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.057 ng/mL

MBP High Sensitivity ELISA Kit (Human) (OKCD01323)

OKCD01323 96 Wells
EUR 831
Description: Description of target: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.4 pg/mL

F2 High Sensitivity ELISA Kit (Human) (OKCD01330)

OKCD01330 96 Wells
EUR 831
Description: Description of target: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.08 pg/mL

APC High Sensitivity ELISA Kit (Human) (OKCD01332)

OKCD01332 96 Wells
EUR 831
Description: Description of target: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.4 pg/mL

ORM1 High Sensitivity ELISA Kit (Human) (OKCD01335)

OKCD01335 96 Wells
EUR 648
Description: Description of target: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.41 ng/mL

HP High Sensitivity ELISA Kit (Human) (OKCD01336)

OKCD01336 96 Wells
EUR 609
Description: Description of target: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.102 ng/mL

CRP High Sensitivity ELISA Kit (Human) (OKCD01339)

OKCD01339 96 Wells
EUR 609
Description: Description of target: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 23.3 pg/mL

ALB High Sensitivity ELISA Kit (Human) (OKCD01346)

OKCD01346 96 Wells
EUR 648
Description: Description of target: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.55 ng/mL

LDL High Sensitivity ELISA Kit (Human) (OKCD01347)

OKCD01347 96 Wells
EUR 544
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.35 ng/mL

VGF High Sensitivity ELISA Kit (Human) (OKCD01348)

OKCD01348 96 Wells
EUR 870
Description: Description of target: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.0 pg/mL

LYZ High Sensitivity ELISA Kit (Human) (OKCD01349)

OKCD01349 96 Wells
EUR 870
Description: Description of target: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.3 pg/mL

CTSD High Sensitivity ELISA Kit (Human) (OKCD01351)

OKCD01351 96 Wells
EUR 870
Description: Description of target: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.27 pg/mL

APOB48 High Sensitivity ELISA Kit (Human) (OKCD01355)

OKCD01355 96 Wells
EUR 870
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 1.1 ng/mL

LRG1 High Sensitivity ELISA Kit (Human) (OKCD01356)

OKCD01356 96 Wells
EUR 870
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.113 ng/mL

MAPT High Sensitivity ELISA Kit (Human) (OKCD01360)

OKCD01360 96 Wells
EUR 870
Description: Description of target: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.8 pg/mL

APOB High Sensitivity ELISA Kit (Human) (OKCD01363)

OKCD01363 96 Wells
EUR 740
Description: Description of target: Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.65 ng/mL

S100A4 High Sensitivity ELISA Kit (Human) (OKCD01366)

OKCD01366 96 Wells
EUR 909
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 30 pg/mL

IFNL3 High Sensitivity ELISA Kit (Human) (OKCD01367)

OKCD01367 96 Wells
EUR 909
Description: Description of target: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.55 pg/mL

TRF High Sensitivity ELISA Kit (Human) (OKCD01368)

OKCD01368 96 Wells
EUR 648
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.051 ng/mL

NOG High Sensitivity ELISA Kit (Human) (OKCD01371)

OKCD01371 96 Wells
EUR 1001
Description: Description of target: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.059 ng/mL

APOM High Sensitivity ELISA Kit (Human) (OKCD01372)

OKCD01372 96 Wells
EUR 909
Description: Description of target: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.121 ng/mL

SFRP5 High Sensitivity ELISA Kit (Human) (OKCD01375)

OKCD01375 96 Wells
EUR 909
Description: Description of target: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.51 ng/mL

APOL1 High Sensitivity ELISA Kit (Human) (OKCD01378)

OKCD01378 96 Wells
EUR 909
Description: Description of target: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.112 ng/mL

NEFL High Sensitivity ELISA Kit (Human) (OKCD01380)

OKCD01380 96 Wells
EUR 909
Description: Description of target: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.61 pg/mL

UMOD High Sensitivity ELISA Kit (Human) (OKCD01383)

OKCD01383 96 Wells
EUR 909
Description: Description of target: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia.Curated;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.3 pg/mL

KL High Sensitivity ELISA Kit (Human) (OKCD01384)

OKCD01384 96 Wells
EUR 909
Description: Description of target: May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

PARK7 High Sensitivity ELISA Kit (Human) (OKCD01385)

OKCD01385 96 Wells
EUR 975
Description: Description of target: Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease; functions probably related to its primary function. It is involved in neuroprotective mechanisms like the stabilization of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway. Its involvement in protein repair could also explain other unrelated functions. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. Required for correct mitochondrial morphology and function as well as for autophagy of dysfunctional mitochondria. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Regulates astrocyte inflammatory responses, may modulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Metal-binding protein able to bind copper as well as toxic mercury ions, enhances the cell protection mechanism against induced metal toxicity.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 26.3 pg/mL

ENHO High Sensitivity ELISA Kit (Human) (OKCD01388)

OKCD01388 96 Wells
EUR 975
Description: Description of target: Involved in the regulation of glucose homeostasis and lipid metabolism.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.2 pg/mL

WNT3A High Sensitivity ELISA Kit (Human) (OKCD01389)

OKCD01389 96 Wells
EUR 975
Description: Description of target: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.062 ng/mL

C4d High Sensitivity ELISA Kit (Human) (OKCD01390)

OKCD01390 96 Wells
EUR 975
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.1 pg/mL

OVAL High Sensitivity ELISA Kit (OKCD01353)

OKCD01353 96 Wells
EUR 596
Description: Description of target: Non-inhibitory serpin. Storage protein of egg white.;Species reactivity: pan-species;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: <28 pg/mL

ChromaFlash High-Sensitivity ChIP Kit

P-2027 48 Reactions
EUR 643.05
Description: Ask the seller for details

Human High sensitivity C Reactive Protein ELISA kit

DEIA-BJ553 96T
EUR 748
Description: This CD Human High sensitivity C Reactive Protein ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human High sensitivity C Reactive Protein (hsCRP). This ELISA kit for research use only, not for therapeutic or diag

Human High sensitivity C Reactive Protein ELISA kit

E01C0087-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human High sensitivity C Reactive Protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High sensitivity C Reactive Protein ELISA kit

E01C0087-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human High sensitivity C Reactive Protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High sensitivity C Reactive Protein ELISA kit

E01C0087-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human High sensitivity C Reactive Protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High sensitivity Cardiac Troponin I ELISA kit

E01H0417-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Human High sensitivity Cardiac Troponin I in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High sensitivity Cardiac Troponin I ELISA kit

E01H0417-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Human High sensitivity Cardiac Troponin I in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High sensitivity Cardiac Troponin I ELISA kit

E01H0417-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Human High sensitivity Cardiac Troponin I in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human High Sensitivity Cystatin C (CST3) ELISA Kit

abx250345-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Human high sensitivity C- Reactive Protein ELISA Kit

ELA-E0821h 96 Tests
EUR 824

C5b-9 High Sensitivity ELISA Kit (Human) (OKCD01373)

OKCD01373 96 Wells
EUR 909
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 4.7 pg/mL

IFN gamma High Sensitivity ELISA Kit (Human) (OKDB00041)

OKDB00041 1x96Wells
EUR 787
Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.69 pg/mL

Morphine antibody (High Sensitivity)

10-1379 1 mg
EUR 169
Description: Mouse monoclonal Morphine antibody

TMB Precipitating (High Sensitivity)

TM5125 125 ml
EUR 85

TMB Precipitating (High Sensitivity)

TM5500 500 ml
EUR 138

TMB Precipitating (High Sensitivity)

TM5999 1000 ml
EUR 208

High Sensitivity Polyethylene Glycol (PEG) ELISA Kit

DEIA6158 96T
EUR 1165
Description: High Sensitivity Polyethylene Glycol (PEG) ELISA Kit is High Sensitivity ELISA for the Measurement of PEG and PEGylated Proteins.

Rat High Sensitivity Insulin (INS) ELISA Kit

abx363835-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

IGF1 High Sensitivity ELISA Kit (Dog) (OKCD01300)

OKCD01300 96 Wells
EUR 936
Description: Description of target: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca2+-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.;Species reactivity: Dog;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

Il10 High Sensitivity ELISA Kit (Mouse) (OKCD01301)

OKCD01301 96 Wells
EUR 870
Description: Description of target: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.43 pg/mL

Il1a High Sensitivity ELISA Kit (Mouse) (OKCD01303)

OKCD01303 96 Wells
EUR 909
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.03 pg/mL

Il1a High Sensitivity ELISA Kit (Rat) (OKCD01304)

OKCD01304 96 Wells
EUR 740
Description: Description of target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.8 pg/mL

IL6 High Sensitivity ELISA Kit (Bovine) (OKCD01306)

OKCD01306 96 Wells
EUR 936
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.45 pg/mL

IL6 High Sensitivity ELISA Kit (Goat) (OKCD01307)

OKCD01307 96 Wells
EUR 1040
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Goat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.138 pg/mL

IL6 High Sensitivity ELISA Kit (Sheep) (OKCD01309)

OKCD01309 96 Wells
EUR 1027
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Sheep;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.46 pg/mL

Il6 High Sensitivity ELISA Kit (Rat) (OKCD01310)

OKCD01310 96 Wells
EUR 609
Description: Description of target: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.47 pg/mL

MMP1 High Sensitivity ELISA Kit (Rabbit) (OKCD01313)

OKCD01313 96 Wells
EUR 896
Description: Description of target: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. ;Species reactivity: Rabbit;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.5 pg/mL

Mmp13 High Sensitivity ELISA Kit (Mouse) (OKCD01315)

OKCD01315 96 Wells
EUR 844
Description: Description of target: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 6.3 pg/mL

Cxcl12 High Sensitivity ELISA Kit (Rat) (OKCD01317)

OKCD01317 96 Wells
EUR 896
Description: Description of target: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.5 pg/mL

IFNB High Sensitivity ELISA Kit (Chicken) (OKCD01319)

OKCD01319 96 Wells
EUR 896
Description: Description of target: Has antiviral activities. ;Species reactivity: Chicken;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.16 pg/mL

IgG High Sensitivity ELISA Kit (Bovine) (OKCD01324)

OKCD01324 96 Wells
EUR 740
Description: Description of target: ;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.083 ng/mL

IgG High Sensitivity ELISA Kit (Mouse) (OKCD01326)

OKCD01326 96 Wells
EUR 648
Description: Description of target: ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.26 ng/mL

MMP9 High Sensitivity ELISA Kit (Horse) (OKCD01327)

OKCD01327 96 Wells
EUR 975
Description: Description of target: ;Species reactivity: Horse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.9 pg/mL

IL1B High Sensitivity ELISA Kit (Rabbit) (OKCD01328)

OKCD01328 96 Wells
EUR 701
Description: Description of target: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.;Species reactivity: Rabbit;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.21 pg/mL

Casp3 High Sensitivity ELISA Kit (Rat) (OKCD01329)

OKCD01329 96 Wells
EUR 896
Description: Description of target: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 5.3 pg/mL

Most importantly, T cells that are activated by e-tumors / FCS can produce high levels of IFN-γ, produce special CTL induction augmented muc1. Collectively, our results describe the synergy between all tumor cells treated with ethanol and DCS is stimulated dual TLR in pushing augmented CTL responses in vitro by FC preparation. The alternative system is simple and can provide a platform for adoption immunotherapy.

 

 

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