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Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.

Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.
Posted by Curtis

dendritic cell (DC) based vaccine is a promising strategy for cancer immunotherapy. However, clinical trials have shown only limited efficacy, demonstrates the need to optimize protocols for Human DC vaccine preparation. In this study, we systematically compared five different Human vaccines DC maturation protocols used in clinical trials: (1) four-cytokine cocktail (TNF-α, IL -6, IL -1β, and PGE2); (2) cocktails α-DC-cytokine (TNF-α, IL -1β, IFN-α, IFN-γ, and poly I: C); (3) lipopolysaccharide (LPS) / IFN-γ; (4) TNF-α and PGE2; and (5) Trimix (mRNA encoding CD40L, CD70, and constitutively activated Toll-like receptor 4 electroporated into immature DC).

We found that four cytokine cocktail induced high levels of costimulatory and HLA molecules, and CCR7, in DC. Mature DC (MDCs) matured with a cocktail of four cytokines have higher viability than those obtained with other protocols. Based on these features, we chose four cytokine cocktail protocols to further enhance the ability of immunization of DC by introducing exogenous genes. We show that the introduction of exogenous Bcl-2 increased DC survival. Furthermore, introducing the IL – 12p70 rescued inhibition of IL -12 secretion by PGE2 without damaging the DC phenotype.

Introducing both Bcl-2 and IL – 12p70 mRNA into DC induced enhanced cytomegalovirus pp65-specific CD8 + T cells secreting IFN-γ and TNF-α , Taken together, our data demonstrate that DCs matured by a cocktail of four cytokines combined with exogenous Bcl-2 and IL – 12p70 gene expression is a promising approach for clinical applications in cancer immunotherapy.

Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.
Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.

Mycobacterium avium subsp. paratuberculosis MAP1889c Protein Induces Maturation of Dendritic cells and Th2-biased Drives Immune Responses.

Mycobacterium avium subsp . paratuberculosis (MAP) is the causative agent of chronic granulomatous bowel disease in animals and is associated with various autoimmune diseases in Human including Crohn’s disease. A good understanding of host-protective immune response and antibacterial immunity is controlled by MAP and its components may contribute to the development of effective control strategies.

MAP1889c seroreactive identified as an antigen in patients with Crohn’s disease. In this study, we investigated the immunological function of MAP1889c in dendritic cells (DC). MAP1889c stimulated DC to increase the expression of molecular co-stimulatory (CD80 and CD86) and molecular complex class major histocompatibility (MHC) and the secret interleukin higher ( IL ) – 10 and moderate IL -6, tumor necrosis factor (TNF) -α, and IL – 12p70 level through Toll-like receptor (TLR) 4 lanes.

MAP1889c-induced DC activation mediated by mitogen-activated protein kinases (MAPKs), cAMPp-response element binding protein (CREB), and nuclear factor kappa B (NF-kB). In particular, the signal is essential for MAP1889c CREB-mediated IL -10 production but not TNF-α and IL – 12p70 . In addition, DC-mature MAP1889c induced T cell proliferation and drove Th2 response.

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-c-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-c-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Eq-48T 48T
EUR 603.6
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Eq-96T 96T
EUR 784.8
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-g-48T 48T
EUR 603.6
Description: A sandwich quantitative ELISA assay kit for detection of Goat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-g-96T 96T
EUR 784.8
Description: A sandwich quantitative ELISA assay kit for detection of Goat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Hu-48T 48T
EUR 510
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Hu-96T 96T
EUR 657.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Mu-48T 48T
EUR 522
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Mu-96T 96T
EUR 673.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-p-48T 48T
EUR 591.6
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-p-96T 96T
EUR 769.2
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Ra-48T 48T
EUR 387.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Ra-96T 96T
EUR 488.4
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Rb-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Rb-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-b-48Tests 48 Tests
EUR 619.2

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-b-96Tests 96 Tests
EUR 859.2

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-c-48Tests 48 Tests
EUR 591.6

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-c-96Tests 96 Tests
EUR 819.6

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Eq-48Tests 48 Tests
EUR 633.6

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Eq-96Tests 96 Tests
EUR 879.6

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-g-48Tests 48 Tests
EUR 633.6

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-g-96Tests 96 Tests
EUR 879.6

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Hu-48Tests 48 Tests
EUR 523.2

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Hu-96Tests 96 Tests
EUR 721.2

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Mu-48Tests 48 Tests
EUR 536.4

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Mu-96Tests 96 Tests
EUR 741.6

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-p-48Tests 48 Tests
EUR 619.2

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-p-96Tests 96 Tests
EUR 859.2

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Ra-48Tests 48 Tests
EUR 378

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Ra-96Tests 96 Tests
EUR 514.8

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Rb-48Tests 48 Tests
EUR 564

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Rb-96Tests 96 Tests
EUR 781.2

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-b-48Tests 48 Tests
EUR 592.8

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-b-96Tests 96 Tests
EUR 820.8

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-c-48Tests 48 Tests
EUR 566.4

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-c-96Tests 96 Tests
EUR 783.6

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Eq-48Tests 48 Tests
EUR 606

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Eq-96Tests 96 Tests
EUR 840

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-g-48Tests 48 Tests
EUR 606

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-g-96Tests 96 Tests
EUR 840

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Hu-48Tests 48 Tests
EUR 501.6

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Hu-96Tests 96 Tests
EUR 690

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Mu-48Tests 48 Tests
EUR 514.8

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Mu-96Tests 96 Tests
EUR 709.2

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-p-48Tests 48 Tests
EUR 592.8

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-p-96Tests 96 Tests
EUR 820.8

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Ra-48Tests 48 Tests
EUR 362.4

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Ra-96Tests 96 Tests
EUR 493.2

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Rb-48Tests 48 Tests
EUR 540

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Rb-96Tests 96 Tests
EUR 746.4

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Gu-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 1 Alpha (IL1a) in samples from serum, plasma or other biological fluids.

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Gu-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 1 Alpha (IL1a) in samples from serum, plasma or other biological fluids.

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Gu-48Tests 48 Tests
EUR 591.6

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Gu-96Tests 96 Tests
EUR 819.6

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Gu-48Tests 48 Tests
EUR 566.4

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Gu-96Tests 96 Tests
EUR 783.6

Human Interleukin-1 alpha (IL1A)

1-CSB-RP065654h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Interleukin-1 alpha(IL1A) expressed in E.coli

Human Interleukin-1 alpha (IL1A)

1-CSB-RP065694h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Interleukin-1 alpha(IL1A) expressed in E.coli

Human Interleukin-1 alpha (IL1A)

1-CSB-YP011613HUc7
  • EUR 516.00
  • EUR 280.80
  • EUR 1809.60
  • EUR 770.40
  • EUR 1210.80
  • EUR 349.20
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Interleukin-1 alpha(IL1A) expressed in Yeast

Interleukin 1 Alpha (IL1a) Antibody

20-abx132312
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101885
  • EUR 543.60
  • EUR 159.60
  • EUR 1579.20
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101886
  • EUR 376.80
  • EUR 159.60
  • EUR 978.00
  • EUR 510.00
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101887
  • EUR 360.00
  • EUR 159.60
  • EUR 910.80
  • EUR 477.60
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx101888
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101889
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101890
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101891
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101892
  • EUR 543.60
  • EUR 159.60
  • EUR 1579.20
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx104904
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx001782
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx109930
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx131946
  • EUR 427.20
  • EUR 1111.20
  • EUR 560.40
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx131947
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx131948
  • EUR 360.00
  • EUR 844.80
  • EUR 427.20
  • EUR 184.80
  • EUR 292.80
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131949
  • EUR 427.20
  • EUR 1111.20
  • EUR 560.40
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131950
  • EUR 427.20
  • EUR 1111.20
  • EUR 560.40
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131951
  • EUR 410.40
  • EUR 1045.20
  • EUR 543.60
  • EUR 184.80
  • EUR 326.40
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx128132
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx113230
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Interleukin 1 Alpha (IL1a) Antibody

20-abx129396
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx129503
  • EUR 360.00
  • EUR 159.60
  • EUR 927.60
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

abx011004-100ul 100 ul
EUR 493.2

Interleukin 1 Alpha (IL1A) Antibody

abx018000-100ug 100 ug
EUR 460.8

Interleukin 1 Alpha (IL1A) Antibody

abx033027-400ul 400 ul
EUR 627.6

Interleukin 1 Alpha (IL1A) Antibody

abx033027-80l 80 µl
EUR 343.2

Interleukin 1 Alpha (IL1A) Antibody

abx036412-100ug 100 ug
EUR 469.2

Interleukin-1 Alpha (IL1A) Antibody

20-abx225241
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx300512
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx326469
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx210848
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx211106
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Interleukin 1 Alpha (IL1a) Antibody

20-abx173020
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173021
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173022
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173023
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173024
  • EUR 1144.80
  • EUR 577.20
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx177052
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx177054
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx177055
  • EUR 1646.40
  • EUR 777.60
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine)

4-PAA071Bo01
  • EUR 310.80
  • EUR 3241.20
  • EUR 801.60
  • EUR 392.40
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog)

4-PAA071Ca01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog)

4-PAA071Ca02
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat)

4-PAA071Cp01
  • EUR 315.60
  • EUR 3312.00
  • EUR 818.40
  • EUR 398.40
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse)

4-PAA071Eq01
  • EUR 315.60
  • EUR 3312.00
  • EUR 818.40
  • EUR 398.40
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Human)

4-PAA071Hu01
  • EUR 278.40
  • EUR 2742.00
  • EUR 688.80
  • EUR 346.80
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Human)

4-PAA071Hu02
  • EUR 278.40
  • EUR 2726.40
  • EUR 685.20
  • EUR 345.60
  • EUR 248.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Mouse)

4-PAA071Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Mouse)

4-PAA071Mu02
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Pig)

4-PAA071Po01
  • EUR 310.80
  • EUR 3232.80
  • EUR 800.40
  • EUR 391.20
  • EUR 261.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Rat)

4-PAA071Ra01
  • EUR 230.40
  • EUR 1982.40
  • EUR 516.00
  • EUR 278.40
  • EUR 228.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Rabbit)

4-PAA071Rb51
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Guinea polyclonal antibody against Rabbit Interleukin 1 Alpha (IL1a)

Macaca mulatta Interleukin-1 alpha (IL1A)

1-CSB-YP011613MOW
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Macaca mulatta Interleukin-1 alpha(IL1A) expressed in Yeast

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), APC

4-PAA071Bo01-APC
  • EUR 435.60
  • EUR 4243.20
  • EUR 1172.40
  • EUR 559.20
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), Biotinylated

4-PAA071Bo01-Biotin
  • EUR 388.80
  • EUR 3181.20
  • EUR 930.00
  • EUR 480.00
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), Cy3

4-PAA071Bo01-Cy3
  • EUR 531.60
  • EUR 5607.60
  • EUR 1514.40
  • EUR 694.80
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), FITC

4-PAA071Bo01-FITC
  • EUR 372.00
  • EUR 3417.60
  • EUR 962.40
  • EUR 470.40
  • EUR 241.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), HRP

4-PAA071Bo01-HRP
  • EUR 397.20
  • EUR 3697.20
  • EUR 1036.80
  • EUR 504.00
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), PE

4-PAA071Bo01-PE
  • EUR 372.00
  • EUR 3417.60
  • EUR 962.40
  • EUR 470.40
  • EUR 241.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), APC

4-PAA071Ca01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Biotinylated

4-PAA071Ca01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Cy3

4-PAA071Ca01-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), FITC

4-PAA071Ca01-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), HRP

4-PAA071Ca01-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), PE

4-PAA071Ca01-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), APC

4-PAA071Ca02-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Biotinylated

4-PAA071Ca02-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Cy3

4-PAA071Ca02-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), FITC

4-PAA071Ca02-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), HRP

4-PAA071Ca02-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), PE

4-PAA071Ca02-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), APC

4-PAA071Cp01-APC
  • EUR 442.80
  • EUR 4340.40
  • EUR 1197.60
  • EUR 568.80
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), Biotinylated

4-PAA071Cp01-Biotin
  • EUR 394.80
  • EUR 3252.00
  • EUR 948.00
  • EUR 487.20
  • EUR 271.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), Cy3

4-PAA071Cp01-Cy3
  • EUR 541.20
  • EUR 5737.20
  • EUR 1546.80
  • EUR 708.00
  • EUR 316.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), FITC

4-PAA071Cp01-FITC
  • EUR 378.00
  • EUR 3495.60
  • EUR 981.60
  • EUR 478.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), HRP

4-PAA071Cp01-HRP
  • EUR 404.40
  • EUR 3781.20
  • EUR 1057.20
  • EUR 512.40
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), PE

4-PAA071Cp01-PE
  • EUR 378.00
  • EUR 3495.60
  • EUR 981.60
  • EUR 478.80
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), APC

4-PAA071Eq01-APC
  • EUR 442.80
  • EUR 4340.40
  • EUR 1197.60
  • EUR 568.80
  • EUR 274.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), Biotinylated

4-PAA071Eq01-Biotin
  • EUR 394.80
  • EUR 3252.00
  • EUR 948.00
  • EUR 487.20
  • EUR 271.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), Cy3

4-PAA071Eq01-Cy3
  • EUR 541.20
  • EUR 5737.20
  • EUR 1546.80
  • EUR 708.00
  • EUR 316.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Production of lipopolysaccharide (LPS) -mediated pro-inflammatory cytokines and anti-inflammatory cytokine is suppressed and increased respectively by MAP1889c pretreatment in DC and T cells addition, treatment MAP1889c in M. avium -infected macrophages promoted the growth of intracellular bacteria and IL -10 production. These findings indicate that MAP1889c antimycobacterial modulate the host response and can be a potential virulence factor for MAP infection.

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