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Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.

Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.
Posted by Curtis

dendritic cell (DC) based vaccine is a promising strategy for cancer immunotherapy. However, clinical trials have shown only limited efficacy, demonstrates the need to optimize protocols for Human DC vaccine preparation. In this study, we systematically compared five different Human vaccines DC maturation protocols used in clinical trials: (1) four-cytokine cocktail (TNF-α, IL -6, IL -1β, and PGE2); (2) cocktails α-DC-cytokine (TNF-α, IL -1β, IFN-α, IFN-γ, and poly I: C); (3) lipopolysaccharide (LPS) / IFN-γ; (4) TNF-α and PGE2; and (5) Trimix (mRNA encoding CD40L, CD70, and constitutively activated Toll-like receptor 4 electroporated into immature DC).

We found that four cytokine cocktail induced high levels of costimulatory and HLA molecules, and CCR7, in DC. Mature DC (MDCs) matured with a cocktail of four cytokines have higher viability than those obtained with other protocols. Based on these features, we chose four cytokine cocktail protocols to further enhance the ability of immunization of DC by introducing exogenous genes. We show that the introduction of exogenous Bcl-2 increased DC survival. Furthermore, introducing the IL – 12p70 rescued inhibition of IL -12 secretion by PGE2 without damaging the DC phenotype.

Introducing both Bcl-2 and IL – 12p70 mRNA into DC induced enhanced cytomegalovirus pp65-specific CD8 + T cells secreting IFN-γ and TNF-α , Taken together, our data demonstrate that DCs matured by a cocktail of four cytokines combined with exogenous Bcl-2 and IL – 12p70 gene expression is a promising approach for clinical applications in cancer immunotherapy.

Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.
Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.

Mycobacterium avium subsp. paratuberculosis MAP1889c Protein Induces Maturation of Dendritic cells and Th2-biased Drives Immune Responses.

Mycobacterium avium subsp . paratuberculosis (MAP) is the causative agent of chronic granulomatous bowel disease in animals and is associated with various autoimmune diseases in Human including Crohn’s disease. A good understanding of host-protective immune response and antibacterial immunity is controlled by MAP and its components may contribute to the development of effective control strategies.

MAP1889c seroreactive identified as an antigen in patients with Crohn’s disease. In this study, we investigated the immunological function of MAP1889c in dendritic cells (DC). MAP1889c stimulated DC to increase the expression of molecular co-stimulatory (CD80 and CD86) and molecular complex class major histocompatibility (MHC) and the secret interleukin higher ( IL ) – 10 and moderate IL -6, tumor necrosis factor (TNF) -α, and IL – 12p70 level through Toll-like receptor (TLR) 4 lanes.

MAP1889c-induced DC activation mediated by mitogen-activated protein kinases (MAPKs), cAMPp-response element binding protein (CREB), and nuclear factor kappa B (NF-kB). In particular, the signal is essential for MAP1889c CREB-mediated IL -10 production but not TNF-α and IL – 12p70 . In addition, DC-mature MAP1889c induced T cell proliferation and drove Th2 response.

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-c-48Tests 48 Tests
EUR 472

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-c-96Tests 96 Tests
EUR 653

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Eq-48Tests 48 Tests
EUR 505

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Eq-96Tests 96 Tests
EUR 700

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-g-48Tests 48 Tests
EUR 505

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-g-96Tests 96 Tests
EUR 700

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Hu-48Tests 48 Tests
EUR 418

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Hu-96Tests 96 Tests
EUR 575

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Mu-48Tests 48 Tests
EUR 429

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Mu-96Tests 96 Tests
EUR 591

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-p-48Tests 48 Tests
EUR 494

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-p-96Tests 96 Tests
EUR 684

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Ra-48Tests 48 Tests
EUR 302

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Ra-96Tests 96 Tests
EUR 411

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Rb-48Tests 48 Tests
EUR 450

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Rb-96Tests 96 Tests
EUR 622

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-b-48T 48T
EUR 493
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-b-96T 96T
EUR 641
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-c-48T 48T
EUR 474
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-c-96T 96T
EUR 614
Description: A sandwich quantitative ELISA assay kit for detection of Canine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Eq-48T 48T
EUR 503
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Eq-96T 96T
EUR 654
Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-g-48T 48T
EUR 503
Description: A sandwich quantitative ELISA assay kit for detection of Goat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-g-96T 96T
EUR 654
Description: A sandwich quantitative ELISA assay kit for detection of Goat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Hu-48T 48T
EUR 425
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Hu-96T 96T
EUR 548
Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Mu-48T 48T
EUR 435
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Mu-96T 96T
EUR 561
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-p-48T 48T
EUR 493
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-p-96T 96T
EUR 641
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Ra-48T 48T
EUR 323
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Ra-96T 96T
EUR 407
Description: A sandwich quantitative ELISA assay kit for detection of Rat Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Rb-48T 48T
EUR 454
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Rb-96T 96T
EUR 587
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 1 Alpha (IL1a) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-b-48Tests 48 Tests
EUR 516

Bovine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-b-96Tests 96 Tests
EUR 716

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-c-48Tests 48 Tests
EUR 493

Canine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-c-96Tests 96 Tests
EUR 683

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Eq-48Tests 48 Tests
EUR 528

Equine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Eq-96Tests 96 Tests
EUR 733

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-g-48Tests 48 Tests
EUR 528

Goat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-g-96Tests 96 Tests
EUR 733

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Hu-48Tests 48 Tests
EUR 436

Human Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Hu-96Tests 96 Tests
EUR 601

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Mu-48Tests 48 Tests
EUR 447

Mouse Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Mu-96Tests 96 Tests
EUR 618

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-p-48Tests 48 Tests
EUR 516

Porcine Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-p-96Tests 96 Tests
EUR 716

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Ra-48Tests 48 Tests
EUR 315

Rat Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Ra-96Tests 96 Tests
EUR 429

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Rb-48Tests 48 Tests
EUR 470

Rabbit Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Rb-96Tests 96 Tests
EUR 651

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Gu-48Tests 48 Tests
EUR 472

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RD-IL1a-Gu-96Tests 96 Tests
EUR 653

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Gu-48T 48T
EUR 474
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 1 Alpha (IL1a) in samples from serum, plasma or other biological fluids.

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

DLR-IL1a-Gu-96T 96T
EUR 614
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 1 Alpha (IL1a) in samples from serum, plasma or other biological fluids.

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Gu-48Tests 48 Tests
EUR 493

Guinea pig Interleukin 1 Alpha (IL1a) ELISA Kit

RDR-IL1a-Gu-96Tests 96 Tests
EUR 683

Interleukin 1 Alpha (IL1a) Antibody

20-abx128132
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx129396
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx129503
  • EUR 300.00
  • EUR 133.00
  • EUR 773.00
  • EUR 411.00
  • EUR 258.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx109930
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx113230
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx001782
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Interleukin 1 Alpha (IL1a) Antibody

20-abx104904
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101885
  • EUR 453.00
  • EUR 133.00
  • EUR 1316.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101886
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101887
  • EUR 300.00
  • EUR 133.00
  • EUR 759.00
  • EUR 398.00
  • EUR 258.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx101888
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101889
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101890
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101891
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx101892
  • EUR 453.00
  • EUR 133.00
  • EUR 1316.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

abx036412-100ug 100 ug
EUR 391

Interleukin 1 Alpha (IL1a) Antibody

20-abx131946
  • EUR 356.00
  • EUR 926.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx131947
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx131948
  • EUR 300.00
  • EUR 704.00
  • EUR 356.00
  • EUR 154.00
  • EUR 244.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131949
  • EUR 356.00
  • EUR 926.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131950
  • EUR 356.00
  • EUR 926.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx131951
  • EUR 342.00
  • EUR 871.00
  • EUR 453.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx132312
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin 1 Alpha (IL1A) Antibody

abx011004-100ul 100 ul
EUR 411

Interleukin 1 Alpha (IL1A) Antibody

abx033027-400ul 400 ul
EUR 523

Interleukin 1 Alpha (IL1A) Antibody

abx033027-80l 80 µl
EUR 286

Interleukin 1 Alpha (IL1A) Antibody

abx018000-100ug 100 ug
EUR 384

Interleukin 1 Alpha (IL1A) Antibody

20-abx210848
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx211106
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Interleukin 1 Alpha (IL1a) Antibody

20-abx177052
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx177054
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx177055
  • EUR 1372.00
  • EUR 648.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173020
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173021
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173022
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173023
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1a) Antibody

20-abx173024
  • EUR 954.00
  • EUR 481.00
  • 1 mg
  • 200 ug

Interleukin 1 Alpha (IL1A) Antibody

20-abx300512
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Interleukin-1 Alpha (IL1A) Antibody

20-abx225241
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

Interleukin 1 Alpha (IL1A) Antibody

20-abx326469
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine)

4-PAA071Bo01
  • EUR 259.00
  • EUR 2701.00
  • EUR 668.00
  • EUR 327.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog)

4-PAA071Ca01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog)

4-PAA071Ca02
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat)

4-PAA071Cp01
  • EUR 263.00
  • EUR 2760.00
  • EUR 682.00
  • EUR 332.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse)

4-PAA071Eq01
  • EUR 263.00
  • EUR 2760.00
  • EUR 682.00
  • EUR 332.00
  • EUR 220.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Human)

4-PAA071Hu01
  • EUR 232.00
  • EUR 2285.00
  • EUR 574.00
  • EUR 289.00
  • EUR 208.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Human)

4-PAA071Hu02
  • EUR 232.00
  • EUR 2272.00
  • EUR 571.00
  • EUR 288.00
  • EUR 207.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Mouse)

4-PAA071Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Mouse)

4-PAA071Mu02
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Pig)

4-PAA071Po01
  • EUR 259.00
  • EUR 2694.00
  • EUR 667.00
  • EUR 326.00
  • EUR 218.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Pig Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Rat)

4-PAA071Ra01
  • EUR 192.00
  • EUR 1652.00
  • EUR 430.00
  • EUR 232.00
  • EUR 190.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Rabbit)

4-PAA071Rb51
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Guinea polyclonal antibody against Rabbit Interleukin 1 Alpha (IL1a)

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), APC

4-PAA071Bo01-APC
  • EUR 363.00
  • EUR 3536.00
  • EUR 977.00
  • EUR 466.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), Biotinylated

4-PAA071Bo01-Biotin
  • EUR 324.00
  • EUR 2651.00
  • EUR 775.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), Cy3

4-PAA071Bo01-Cy3
  • EUR 443.00
  • EUR 4673.00
  • EUR 1262.00
  • EUR 579.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), FITC

4-PAA071Bo01-FITC
  • EUR 310.00
  • EUR 2848.00
  • EUR 802.00
  • EUR 392.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), HRP

4-PAA071Bo01-HRP
  • EUR 331.00
  • EUR 3081.00
  • EUR 864.00
  • EUR 420.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Bovine), PE

4-PAA071Bo01-PE
  • EUR 310.00
  • EUR 2848.00
  • EUR 802.00
  • EUR 392.00
  • EUR 201.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Bovine Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), APC

4-PAA071Ca01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Biotinylated

4-PAA071Ca01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Cy3

4-PAA071Ca01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), FITC

4-PAA071Ca01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), HRP

4-PAA071Ca01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), PE

4-PAA071Ca01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), APC

4-PAA071Ca02-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Biotinylated

4-PAA071Ca02-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), Cy3

4-PAA071Ca02-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), FITC

4-PAA071Ca02-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), HRP

4-PAA071Ca02-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Dog), PE

4-PAA071Ca02-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Dog Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), APC

4-PAA071Cp01-APC
  • EUR 369.00
  • EUR 3617.00
  • EUR 998.00
  • EUR 474.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), Biotinylated

4-PAA071Cp01-Biotin
  • EUR 329.00
  • EUR 2710.00
  • EUR 790.00
  • EUR 406.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), Cy3

4-PAA071Cp01-Cy3
  • EUR 451.00
  • EUR 4781.00
  • EUR 1289.00
  • EUR 590.00
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), FITC

4-PAA071Cp01-FITC
  • EUR 315.00
  • EUR 2913.00
  • EUR 818.00
  • EUR 399.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), HRP

4-PAA071Cp01-HRP
  • EUR 337.00
  • EUR 3151.00
  • EUR 881.00
  • EUR 427.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Goat), PE

4-PAA071Cp01-PE
  • EUR 315.00
  • EUR 2913.00
  • EUR 818.00
  • EUR 399.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Goat Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), APC

4-PAA071Eq01-APC
  • EUR 369.00
  • EUR 3617.00
  • EUR 998.00
  • EUR 474.00
  • EUR 229.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with APC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), Biotinylated

4-PAA071Eq01-Biotin
  • EUR 329.00
  • EUR 2710.00
  • EUR 790.00
  • EUR 406.00
  • EUR 226.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with Biotin.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), Cy3

4-PAA071Eq01-Cy3
  • EUR 451.00
  • EUR 4781.00
  • EUR 1289.00
  • EUR 590.00
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with Cy3.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), FITC

4-PAA071Eq01-FITC
  • EUR 315.00
  • EUR 2913.00
  • EUR 818.00
  • EUR 399.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with FITC.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), HRP

4-PAA071Eq01-HRP
  • EUR 337.00
  • EUR 3151.00
  • EUR 881.00
  • EUR 427.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with HRP.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Horse), PE

4-PAA071Eq01-PE
  • EUR 315.00
  • EUR 2913.00
  • EUR 818.00
  • EUR 399.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Horse Interleukin 1 Alpha (IL1a). This antibody is labeled with PE.

Interleukin 1 Alpha (IL1a) Polyclonal Antibody (Guinea pig)

4-PAA071Gu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Guinea pig Interleukin 1 Alpha (IL1a)

Production of lipopolysaccharide (LPS) -mediated pro-inflammatory cytokines and anti-inflammatory cytokine is suppressed and increased respectively by MAP1889c pretreatment in DC and T cells addition, treatment MAP1889c in M. avium -infected macrophages promoted the growth of intracellular bacteria and IL -10 production. These findings indicate that MAP1889c antimycobacterial modulate the host response and can be a potential virulence factor for MAP infection.

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